Studying human nociceptors: from fundamentals to clinic

Chronic pain affects one in five of the general population and is the third most important cause of disability-adjusted life-years globally. Unfortunately, treatment remains inadequate due to poor efficacy and tolerability. There has been a failure in translating promising preclinical drug targets i...

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Bibliographic Details

Published in:	Brain (London, England : 1878) Vol. 144; no. 5; pp. 1312 - 1335
Main Authors:	Middleton, Steven J, Barry, Allison M, Comini, Maddalena, Li, Yan, Ray, Pradipta R, Shiers, Stephanie, Themistocleous, Andreas C, Uhelski, Megan L, Yang, Xun, Dougherty, Patrick M, Price, Theodore J, Bennett, David L
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 22-06-2021
Subjects:	Animals Chronic Pain - physiopathology Humans Nociceptors - physiology Review Translational Research, Biomedical transcriptomics nociceptors IPSC derived nociceptors microneurography patch-clamp
Online Access:	Get full text
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