The role of catecholamine innervation in the medial prefrontal cortex on the regulation of body weight and food intake

•6-OHDA lesion was carried out in the medial prefrontal cortex.•Catecholamine lesions of the medial prefrontal cortex reduced body weight.•Catecholamine lesions disrupted habituation in the open field.•Lesion of dopamine terminals augmented hunger-induced feeding.•Lesion of dopamine terminals led to...

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Bibliographic Details
Published in:	Behavioural brain research Vol. 286; pp. 318 - 327
Main Authors:	Gálosi, Rita, Hajnal, Andras, Petykó, Zoltán, Hartmann, Géza, Karádi, Zoltán, Lénárd, László
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-06-2015
Subjects:	Adrenergic Agents - toxicity Animals Body weight Body Weight - physiology Catecholamine Dopamine - metabolism Drinking Water - administration & dosage Eating - physiology Exploratory Behavior - physiology Food Preferences - physiology Glucose - administration & dosage Glucose preference Habituation, Psychophysiologic - physiology Male Medial prefrontal cortex Motor Activity - physiology Norepinephrine - metabolism Oxidopamine - toxicity Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Prefrontal Cortex - pathology Rats, Wistar Tyrosine 3-Monooxygenase - metabolism DMI Medial prefrontal cortex Body weight NE 6-OHDA PFC Catecholamine DA HPLC Glucose preference
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