Successful treatment of mediastinal seminoma with vinblastine, bleomycin, and cis-platinum

We report on 2 patients with extensive primary mediastinal seminoma treated with vinblastine, bleomycin, and cis-dichlorodiammine platinum who achieved complete remission. These patients are alive forty-six months and sixty-six months without evidence of recurrence of disease. These long-term surviv...

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Bibliographic Details
Published in:	Urology (Ridgewood, N.J.) Vol. 22; no. 6; p. 640
Main Authors:	Clamon, G H, Loening, S, Stump, D, River, G, Corder, M
Format:	Journal Article
Language:	English
Published:	United States 01-12-1983
Subjects:	Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bleomycin - administration & dosage Cisplatin - administration & dosage Dysgerminoma - drug therapy Humans Male Mediastinal Neoplasms - drug therapy Vinblastine - administration & dosage
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Summary:	We report on 2 patients with extensive primary mediastinal seminoma treated with vinblastine, bleomycin, and cis-dichlorodiammine platinum who achieved complete remission. These patients are alive forty-six months and sixty-six months without evidence of recurrence of disease. These long-term survivors extend the experience reported previously in the literature. Mediastinal seminoma with extent beyond a rational field of radiation therapy can be treated successfully with chemotherapy.
ISSN:	0090-4295
DOI:	10.1016/0090-4295(83)90316-3