Clinical chemical indexes and severity of coronary atherosclerosis

The present study measured triglycerides (TG), total cholesterol (TC), HDL-cholesterol (HDL-C), LDL and LDL/HDL-C, TC/HDL-C and HDL-C/TC. 100 ratios in 261 men and women undergoing coronary arteriography. The results show that TG, TC, HDL-C and LDL levels are not related to the severity of coronary...

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Bibliographic Details
Published in:	Clinica chimica acta Vol. 130; no. 3; p. 283
Main Authors:	Lippi, U, Cappelletti, P, Signori, D, Burelli, C
Format:	Journal Article
Language:	English
Published:	Netherlands 15-06-1983
Subjects:	Adult Aged Cholesterol - blood Cholesterol, HDL Cholesterol, LDL Coronary Disease - blood Female Humans Lipoproteins - blood Lipoproteins, HDL - blood Lipoproteins, LDL - blood Male Middle Aged Triglycerides - blood
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Summary:	The present study measured triglycerides (TG), total cholesterol (TC), HDL-cholesterol (HDL-C), LDL and LDL/HDL-C, TC/HDL-C and HDL-C/TC. 100 ratios in 261 men and women undergoing coronary arteriography. The results show that TG, TC, HDL-C and LDL levels are not related to the severity of coronary artery disease (CAD). The LDL/HDL-C, TC/HDL-C and HDL/TC.100 ratios are statistically related to the severity of CAD. The LDL/HDL-C ratio appeared to be the most sensitive index for reflecting CAD of mild severity with a predictive value of 83.3% at 76.6% specificity and at 77.7% sensitivity (cut-off: 3.20). Average values of LDL and HDL-C alone are not reliable indices of mild severity CAD.
ISSN:	0009-8981
DOI:	10.1016/0009-8981(83)90302-9