A radical view of gallstone aetiogenesis

It is proposed that gallstones stem from insufficiency of micronutrient antioxidants relative to the load of oxidants and/or oxidation-prone substrates within hepatocytes in such a way that ancillary hepatobiliary resources, including bilirubin with lactoferrin and mucin, are mobilized to combat oxi...

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Bibliographic Details
Published in:	Medical hypotheses Vol. 45; no. 5; pp. 510 - 516
Main Authors:	Braganza, J.M., Worthington, H.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01-11-1995
Subjects:	Animals Bile - metabolism Cholelithiasis - etiology Cholelithiasis - metabolism Cholelithiasis - prevention & control Cholesterol - metabolism Cytochrome P-450 Enzyme System - metabolism Disease Models, Animal Humans Liver - metabolism Models, Biological Oxidative Stress Pancreas - metabolism Pancreatitis - complications Pancreatitis - metabolism Pigments, Biological - metabolism
Online Access:	Get full text
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