Somatic cell hybrid mapping panels

Somatic cell hybrid mapping panels

The recent advances in human gene mapping have been largely due to the development of interspecies cell hybrids containing human chromosomes and their fragments. The importance of characterized panels of these hybrid lines has grown exponentially with the application of recombinant DNA technologies...

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Bibliographic Details
Published in:Experimental cell research Vol. 152; no. 1; p. 1
Main Authors: Kamarck, M E, Barker, P E, Miller, R L, Ruddle, F H
Format: Journal Article
Language:English
Published: United States 01-05-1984
Subjects:
Animals
Cell Fusion
Cell Line
Cell Transformation, Neoplastic
Chromosome Mapping - methods
Computers
Genes
Genetic Complementation Test
Genetic Markers
Humans
Hybrid Cells
Nucleic Acid Hybridization
Oncogenes
Phenotype
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Description
Summary:The recent advances in human gene mapping have been largely due to the development of interspecies cell hybrids containing human chromosomes and their fragments. The importance of characterized panels of these hybrid lines has grown exponentially with the application of recombinant DNA technologies to human genetics. In this article, we discuss current strategies employed in the construction of somatic cell hybrid mapping panels.
ISSN:0014-4827
DOI:10.1016/0014-4827(84)90224-6