Synthesis, bioevaluation and docking studies of some 2-phenyl-1H-benzimidazole derivatives as anthelminthic agents against the nematode Teladorsagia circumcincta

Gastrointestinal nematode infections are the main diseases in herds of small ruminants. Resistance to the main established drugs has become a worldwide problem. The purpose of this study is to obtain and evaluate the in vitro ovicidal and larvicidal activity of some 2-phenylbenzimidazole derivatives...

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Bibliographic Details

Published in:	European journal of medicinal chemistry Vol. 208; p. 112554
Main Authors:	Escala, Nerea, Valderas-García, Elora, Bardón, María Álvarez, Gómez de Agüero, Verónica Castilla, Escarcena, Ricardo, López-Pérez, José Luis, Rojo-Vázquez, Francisco A., San Feliciano, Arturo, Balaña-Fouce, Rafael, Martínez-Valladares, María, Olmo, Esther del
Format:	Journal Article
Language:	English
Published:	Elsevier Masson SAS 15-12-2020
Subjects:	2-Phenyl-1H-benzimidazoles Cytotoxicity in vitro assays Teladorsagia circumcincta Tubulin docking studies Cytotoxicity 2-Phenyl-1H-benzimidazoles in vitro assays Tubulin docking studies Teladorsagia circumcincta
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