Effects of nateglinide and glibenclamide on postprandial lipid and glucose metabolism in type 2 diabetes

Background Postprandial hyperlipemia and small, dense LDL particles are features of dyslipidemia in type 2 diabetes. The purpose of this study was (1) to determine whether the oral insulinotropic drugs, nateglinide and glibenclamide, can overcome the defect of insulin action to suppress the hepatic...

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Bibliographic Details
Published in:	Diabetes/metabolism research and reviews Vol. 18; no. 6; pp. 484 - 490
Main Authors:	Vakkilainen, Juha, Mero, Niina, Schweizer, Anja, Foley, James E., Taskinen, Marja-Riitta
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-11-2002 Wiley
Subjects:	Adolescent Adult Aged apolipoprotein B Biological and medical sciences Blood Glucose - drug effects Cyclohexanes - pharmacology Cyclohexanes - therapeutic use Data Interpretation, Statistical Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Double-Blind Method Female General and cellular metabolism. Vitamins Glucose - metabolism glyburide Glyburide - pharmacology Glyburide - therapeutic use Humans Hyperlipidemias - drug therapy hypertriglyceridemia Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Lipids - blood Lipoproteins, LDL - blood Lipoproteins, LDL - drug effects Male Medical sciences Middle Aged nateglinide Pharmacology. Drug treatments Phenylalanine - analogs & derivatives Phenylalanine - pharmacology Phenylalanine - therapeutic use Postprandial Period small dense LDL Triglycerides - blood Endocrinopathy Pancreatic hormone glyburide Lipids Hyperlipoproteinemia Lipoprotein Enzymopathy Non insulin dependent diabetes Blood plasma Hypoglycemic agent Adult Hormonal investigation Dyslipemia Glibenclamide Nateglinide Human Postprandial Treatment efficiency small dense LDL Metabolic diseases Insulin Chemotherapy Treatment Hypertriglyceridemia Sulfonylureas Double blind study Elderly apolipoprotein B
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