Evaluation of a lysostaphin-fusion protein as a dry-cow therapy for Staphylococcus aureus mastitis in dairy cattle

This study evaluated the efficacy of a recombinant lysostaphin fused to a protein transduction domain (rLYS-PTD) as a dry-cow therapy for the treatment of experimentally induced chronic, subclinical Staphylococcus aureus mastitis. Twenty-two Holstein dairy cows were experimentally infected with Stap...

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Bibliographic Details
Published in:	Journal of dairy science Vol. 99; no. 6; p. 4638
Main Authors:	Hoernig, K J, Donovan, D M, Pithua, P, Williams, 3rd, F, Middleton, J R
Format:	Journal Article
Language:	English
Published:	United States 01-06-2016
Subjects:	Animals Anti-Bacterial Agents - therapeutic use Anti-Infective Agents, Local - therapeutic use Cattle Female Lysostaphin - therapeutic use Mammary Glands, Animal - drug effects Mammary Glands, Animal - microbiology Mastitis, Bovine - drug therapy Mastitis, Bovine - microbiology Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcal Infections - veterinary Staphylococcus aureus - drug effects Staphylococcus aureus mastitis lysostaphin dry-cow therapy
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