S-methyl cysteine sulfoxide ameliorates duodenal morphological alterations in streptozotocin-induced diabetic rats

•SMCS was able to reduce blood glucose from the diabetic rats.•SMCS mitigated morphological alterations caused by DM1 by preventing duodenal changes in volume and villus length.•The beneficial effects of SMCS administration in the duodenal morphology were at least partially attributed to NF-kB modul...

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Bibliographic Details
Published in:	Tissue & cell Vol. 69; p. 101483
Main Authors:	Castro, Valéria Milena Dantas de, Medeiros, Karina Carla de Paula, Lemos, Licyanne Ingrid Carvalho de, Pedrosa, Lucia de Fátima Campos, Ladd, Fernando Vagner Lobo, Carvalho, Thaís Gomes de, Araújo Júnior, Raimundo Fernandes de, Abreu, Bento João, Farias, Naisandra Bezerra da Silva
Format:	Journal Article
Language:	English
Published:	Scotland Elsevier Ltd 01-04-2021 Elsevier Science Ltd
Subjects:	Amino acids Animals Bcl-2 protein Body Weight - drug effects Caspase-3 Crypts Cysteine Cysteine - analogs & derivatives Cysteine - pharmacology Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - pathology Drinking - drug effects Duodenum Duodenum - drug effects Duodenum - pathology Feeding Behavior - drug effects Histomorphometry Hyperglycemia Immunomodulation Interleukin 10 Intestine Male Metabolic disorders Morphology Mucosa NF-κB protein Rats Rats, Wistar Rodents Small intestine SMCS Statistical methods Streptozocin Sulfoxides Supplements Villus Histomorphometry SMCS Small intestine Diabetes mellitus
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