Effects on reproductive, biochemical and genotoxic parameters of herbicides 2,4-D and glyphosate in silver catfish (Rhamdia quelen)

• Published in: Environmental toxicology and pharmacology Vol. 89; p. 103787
• Main Authors: Bernardi, Fernanda, Lirola, Juliana Roratto, Cestari, Marta Margarete, Bombardelli, Robie Allan
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-01-2022; Elsevier Science Ltd
• Subjects: 2,4-D; 2,4-Dichlorophenoxyacetic Acid - toxicity; Animals; Biomarkers; Catfish; Catfishes - growth & development; Catfishes - physiology; DNA Damage; Female; Fertility - drug effects; Fertilization; Gametes; Gametocytes; Genotoxicity; Glycine - analogs & derivatives; Glycine - toxicity; Glyphosate; Hatching; Herbicides; Herbicides - toxicity; Larva - growth & development; Larvae; Male; Mixtures; Oocytes; Oxidative stress; Oxidative Stress - drug effects; Pesticides; Reproduction; Superoxide dismutase; Water Pollutants, Chemical - toxicity; Gametes; Biomarkers; Oxidative stress; Reproduction; Pesticides
• ISSN: 1382-6689; 1872-7077
• DOI: 10.1016/j.etap.2021.103787

The objective of this work was to evaluate the effects of the herbicides 2,4-D, glyphosate and the mixture of both on oxidative stress, genotoxicity and the rates of fertilization, hatching and larval normality in silver catfish. Exposure to glyphosate and the mixture of herbicides significantly decreased the fertilization of oocytes and the hatching of eggs. The different concentrations of 2,4-D and glyphosate, in addition to the mixture of both, did not affect the rates of larval normality, the activity of CAT, GST, LPO, and PCO. SOD activity was not evident in any of the treatments. Exposure to 2,4-D and the mixture of herbicides caused damage to the genetic material of larvae silver catfish. Our results show that although high concentrations of the herbicides were used, changes caused by them were detected in only some of the tested biomarkers.
•Reducing fertilization and hatching rates are responses to exposure to glyphosate.•2,4-D and glyphosate do not induce oxidative stress in Rhamdia quelen larvae.•Exposure to 2,4-D causes genotoxic effect in silver catfish larvae.