Treatment methods following suicidal self-administration of IV organophosphate: What can additional lipid administration change?

Organic phosphor compounds are highly toxic and life-threatening compounds that are widely used in agriculture, households and gardens worldwide. While oral intakes are observed frequently, toxic effects can also be seen through contract or inhalation. However, toxic cases through the parenteral rou...

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Bibliographic Details
Published in:The American journal of emergency medicine Vol. 35; no. 9; pp. 1388.e3 - 1388.e5
Main Authors: Turkdogan, Kenan Ahmet, Duman, Ali, Avcil, Mucahit, Akoz, Ayhan, Canakcı, Selcuk Eren, Kantekin, Burcak
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-09-2017
Elsevier Limited
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Summary:Organic phosphor compounds are highly toxic and life-threatening compounds that are widely used in agriculture, households and gardens worldwide. While oral intakes are observed frequently, toxic effects can also be seen through contract or inhalation. However, toxic cases through the parenteral route have rarely been reported. We had three main aims: first, to present a male patient who self-administered 2ml of monocrotophos intravenously to commit suicide. Our second goal was to present the current multiple treatment methods, such as fast general support, antidote treatment, lipid emulsion treatment, and plasmapheresis along with the literature. Third, we aimed to emphasize that with these treatments, patients' intensive care needs, intermediate symptoms, and hospitalization periods can be decreased and thus mortality and morbidity increase can be prevented.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2017.06.058