ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study

Microfold (M) cells reside in the intestinal epithelium of Peyer's patches (PP). Their unique ability to take up and transport antigens from the intestinal lumen to the underlying lymphoid tissue is key in the regulation of the gut-associated immune response. Here, we applied a multi-omics appr...

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Bibliographic Details

Published in:	Nucleic acids research Vol. 51; no. 3; pp. 1277 - 1296
Main Authors:	Luna Velez, Maria V, Neikes, Hannah K, Snabel, Rebecca R, Quint, Yarah, Qian, Chen, Martens, Aniek, Veenstra, Gert Jan C, Freeman, Michael R, van Heeringen, Simon J, Vermeulen, Michiel
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 22-02-2023
Subjects:	Animals Cell Differentiation Enterocytes Intestinal Mucosa Intestine, Small M Cells Mice Molecular Biology Multiomics Transcription Factors - metabolism
Online Access:	Get full text
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