Vitamin C exhibits pro-oxidant properties

Vitamin C exhibits pro-oxidant properties

Vitamin C is marketed as a dietary supplement, partly because of its 'antioxidant' properties. However, we report here that vitamin C administered as a dietary supplement to healthy humans exhibits a pro-oxidant, as well as an antioxidant, effect in vivo.

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Bibliographic Details
Published in:Nature (London) Vol. 392; no. 6676; p. 559
Main Authors: Podmore, Ian D, Griffiths, Helen R, Herbert, Karl E, Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph
Format: Journal Article
Language:English
Published: England Nature Publishing Group 09-04-1998
Subjects:
Acids
Adenine - analogs & derivatives
Adenine - analysis
Adult
Antioxidants
Ascorbic Acid - pharmacology
Dietary Supplements
DNA - drug effects
DNA Damage
Female
Gas Chromatography-Mass Spectrometry
Humans
Lymphocytes
Lymphocytes - drug effects
Male
Middle Aged
Oxidants - pharmacology
Oxidative stress
Oxidizing agents
Reactive Oxygen Species
Scientific imaging
Termites
Variance analysis
Vitamin C
United Kingdom > UK
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Description
Summary:Vitamin C is marketed as a dietary supplement, partly because of its 'antioxidant' properties. However, we report here that vitamin C administered as a dietary supplement to healthy humans exhibits a pro-oxidant, as well as an antioxidant, effect in vivo.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0028-0836
1476-4687
DOI:10.1038/33308