Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist

X chromosome inactivation occurs twice during the life cycle of placental mammals. In normal females, one X chromosome in each cell is inactivated early in embryogenesis, while in the male, the X chromosome is inactivated together with the Y chromosome in spermatogenic cells shortly before or during...

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Bibliographic Details
Published in:	Journal of cell science Vol. 115; no. Pt 21; pp. 4097 - 4105
Main Authors:	Turner, James M A, Mahadevaiah, Shantha K, Elliott, David J, Garchon, Henri-Jean, Pehrson, John R, Jaenisch, Rudolf, Burgoyne, Paul S
Format:	Journal Article
Language:	English
Published:	England 01-11-2002
Subjects:	Animals DNA Replication - genetics Dosage Compensation, Genetic Fluorescent Antibody Technique Gene Expression Regulation - genetics Germ Cells - metabolism Histones - genetics Histones - metabolism Male Meiosis - genetics Mice Mice, Knockout RNA, Long Noncoding RNA, Messenger - genetics RNA, Messenger - metabolism RNA, Untranslated - genetics RNA, Untranslated - metabolism Spermatocytes - metabolism Spermatogenesis - genetics Testis - metabolism Transcription Factors - genetics Transcription Factors - metabolism X Chromosome - genetics Y Chromosome - genetics
Online Access:	Get full text
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