Assessment of protamine-induced thrombosis of tumor vessels for cancer therapy using dynamic contrast-enhanced MRI

Since the role of angiogenesis in cancer development has been recognized, the study of anti‐angiogenic or anti‐vascular therapeutic agents has become increasingly important for cancer treatment. Selective thrombosis is one approach towards this goal. Since many types of carcinoma accumulate large nu...

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Bibliographic Details
Published in:	NMR in biomedicine Vol. 15; no. 2; pp. 106 - 113
Main Authors:	Su, Min-Ying, Samoszuk, Michael K., Wang, Jun, Nalcioglu, Orhan
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-04-2002
Subjects:	Adenocarcinoma - blood supply Adenocarcinoma - drug therapy Adenocarcinoma - pathology Animals anti-vascular therapy Blood Vessels - drug effects Blood Vessels - pathology dynamic contrast enhanced MRI Female Heparin Antagonists - therapeutic use histology Magnetic Resonance Imaging - methods protamine Protamines - therapeutic use Rats Rats, Inbred F344 thrombosis Thrombosis - chemically induced
Online Access:	Get full text
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