Leptin levels in gingival crevicular fluid during orthodontic tooth movement
To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement. An upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The co...
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| Published in: | The Angle orthodontist Vol. 80; no. 3; pp. 504 - 508 |
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| Format: | Journal Article |
| Language: | English |
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Edward H Angle Education and Research Foundation, Inc
01-05-2010
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| Abstract | To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement.
An upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The control tooth was included in the orthodontic appliance, but was not subjected to the orthodontic force. GCF sampling from the distal sites of the test and control teeth was done at baseline, 1 hour, 24 hours, and 168 hours.
Leptin concentrations of the test teeth decreased in a time-dependent manner. When compared with the baseline measurement, the decrease was significant at 168 hours (P < .05).
The concentration of leptin in GCF is decreased by orthodontic tooth movement; the results of the present study also suggest that leptin may have been one of the mediators responsible for orthodontic tooth movement. |
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| AbstractList | To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement.
An upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The control tooth was included in the orthodontic appliance, but was not subjected to the orthodontic force. GCF sampling from the distal sites of the test and control teeth was done at baseline, 1 hour, 24 hours, and 168 hours.
Leptin concentrations of the test teeth decreased in a time-dependent manner. When compared with the baseline measurement, the decrease was significant at 168 hours (P < .05).
The concentration of leptin in GCF is decreased by orthodontic tooth movement; the results of the present study also suggest that leptin may have been one of the mediators responsible for orthodontic tooth movement. OBJECTIVESTo test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic tooth movement. MATERIALS AND METHODSAn upper canine requiring distal movement served as the test tooth; the contralateral canine was used as a control tooth. The control tooth was included in the orthodontic appliance, but was not subjected to the orthodontic force. GCF sampling from the distal sites of the test and control teeth was done at baseline, 1 hour, 24 hours, and 168 hours. RESULTSLeptin concentrations of the test teeth decreased in a time-dependent manner. When compared with the baseline measurement, the decrease was significant at 168 hours (P < .05). CONCLUSIONSThe concentration of leptin in GCF is decreased by orthodontic tooth movement; the results of the present study also suggest that leptin may have been one of the mediators responsible for orthodontic tooth movement. |
| Author | Ates, F Nesibe Zihni, Meltem Aydin, Tugba Bulut, Caglar Dilsiz, Alparslan Kiliç, Nihat |
| AuthorAffiliation | e Research Assistant, Department of Biochemistry, Faculty of Medicine, Atatürk University, Erzurum, Turkey a Assistant Professor, Department of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey d Postgraduate Student, Department of Orthodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey b Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey c Postgraduate Student, Department of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey |
| AuthorAffiliation_xml | – name: e Research Assistant, Department of Biochemistry, Faculty of Medicine, Atatürk University, Erzurum, Turkey – name: a Assistant Professor, Department of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey – name: b Assistant Professor, Department of Orthodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey – name: d Postgraduate Student, Department of Orthodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey – name: c Postgraduate Student, Department of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey |
| Author_xml | – sequence: 1 givenname: Alparslan surname: Dilsiz fullname: Dilsiz, Alparslan email: aydilsiz@yahoo.com organization: Department of Periodontology, Atatürk University, Erzurum, Turkey. aydilsiz@yahoo.com – sequence: 2 givenname: Nihat surname: Kiliç fullname: Kiliç, Nihat – sequence: 3 givenname: Tugba surname: Aydin fullname: Aydin, Tugba – sequence: 4 givenname: F Nesibe surname: Ates fullname: Ates, F Nesibe – sequence: 5 givenname: Meltem surname: Zihni fullname: Zihni, Meltem – sequence: 6 givenname: Caglar surname: Bulut fullname: Bulut, Caglar |
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| Snippet | To test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during orthodontic... OBJECTIVESTo test if leptin can be detected in the gingival crevicular fluid (GCF) around moving teeth, and to determine whether any changes occur during... |
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| SubjectTerms | Adolescent Cuspid - pathology Dental Plaque Index Female Follow-Up Studies Gingival Crevicular Fluid - chemistry Gingival Hemorrhage - classification Humans Leptin - analysis Male Original Periodontal Index Periodontal Pocket - classification Prospective Studies Tooth Movement Techniques |
| Title | Leptin levels in gingival crevicular fluid during orthodontic tooth movement |
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