Restoring knee joint kinematics after anterior cruciate ligament injury might inhibit synovial membrane inflammation

Restoring knee joint kinematics after anterior cruciate ligament injury might inhibit synovial membrane inflammation

We developed a novel controlled abnormal joint movement (CAJM) model that controls instability after traditional anterior cruciate ligament transection (ACL-T). We evaluated whether joint instability damping suppresses synovial inflammation in osteoarthritis patients using our new CAJM rat model. We...

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Bibliographic Details
Published in:Sport sciences for health Vol. 15; no. 1; pp. 249 - 253
Main Authors: Murata, Kenji, Kokubun, Takanori, Takayanagi, Kiyomi, Kanemura, Naohiko
Format: Journal Article
Language:English
Published: Milan Springer Milan 01-04-2019
Springer Nature B.V
Subjects:
Cartilage
Cytokines
Human Physiology
Inflammation
Joint and ligament injuries
Kinematics
Knee
Medicine
Medicine & Public Health
Metabolic Diseases
Short Communication
Sports Medicine
Tumor necrosis factor-TNF
United States > US
Knee
Synovitis
Rat model
Joint kinematics
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Summary:We developed a novel controlled abnormal joint movement (CAJM) model that controls instability after traditional anterior cruciate ligament transection (ACL-T). We evaluated whether joint instability damping suppresses synovial inflammation in osteoarthritis patients using our new CAJM rat model. We found that joint instability in rats differed between the ACL-T and CAJM models. Joint instability might contribute to synovitis and inhibit osteoarthritis.
ISSN:1824-7490
1825-1234
DOI:10.1007/s11332-018-0481-y