The insulysin (insulin degrading enzyme) enigma

The insulysin (insulin degrading enzyme) enigma

There are many cellular locations proposed for insulysin, yet there is a lack of a definitive study that clearly establishes within which cellular compartment insulin and amyloid beta peptide hydrolysis occurs. The enigma of the insulin degrading enzyme is explored.

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Bibliographic Details
Published in:Cellular and molecular life sciences : CMLS Vol. 63; no. 21; pp. 2432 - 2434
Main Author: Hersh, L B
Format: Journal Article
Language:English
Published: Switzerland Springer Nature B.V 01-11-2006
Birkhäuser-Verlag
Subjects:
Animals
Cellular biology
Enzymes
Humans
Insulin
Insulin - metabolism
Insulysin - chemistry
Insulysin - genetics
Insulysin - metabolism
Mice
Molecular biology
Receptor, Insulin - metabolism
Visions & Reflections
Online Access:Get full text
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Description
Summary:There are many cellular locations proposed for insulysin, yet there is a lack of a definitive study that clearly establishes within which cellular compartment insulin and amyloid beta peptide hydrolysis occurs. The enigma of the insulin degrading enzyme is explored.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1420-682X
1420-9071
DOI:10.1007/s00018-006-6238-9