Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

RNA interference via the endogenous miRNA pathway regulates gene expression by controlling protein synthesis through post-transcriptional gene silencing. In recent years, miRNA-mediated gene regulation has shown potential for treatment of neurological disorders caused by a toxic gain of function mec...

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Bibliographic Details

Published in:	Journal of visualized experiments no. 138
Main Authors:	Pourshafie, Naemeh, Lee, Philip R, Chen, Ke-Lian, Harmison, George G, Bott, Laura C, Fischbeck, Kenneth H, Rinaldi, Carlo
Format:	Journal Article
Language:	English
Published:	United States MyJove Corporation 10-08-2018
Subjects:	Genetics
Online Access:	Get full text
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