Temperature-programmed capillary electrophoresis for the analysis of high-melting point mutants in thalassemias

The behavior of different sieving polymers for unambiguous determination of point mutations in genomic DNA, based on electrophoresis in thin capillaries, is evaluated. High melters from thalassemia patients are separated by exploiting the principle of denaturing gradient gel electrophoresis, in fact...

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Bibliographic Details

Published in:	Electrophoresis Vol. 18; no. 5; p. 724
Main Authors:	Gelfi, C, Righetti, P G, Travi, M, Fattore, S
Format:	Journal Article
Language:	English
Published:	Germany 1997
Subjects:	beta-Thalassemia - genetics DNA - chemistry DNA - genetics DNA Mutational Analysis Electrophoresis, Capillary - methods Globins - genetics Humans Mutation Nucleic Acid Denaturation Temperature
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