Differential Skewing of Circulating MR1-Restricted and γδ T Cells in Human Psoriasis Vulgaris

Psoriasis vulgaris (PV) is a chronic, recurrent inflammatory dermatosis mediated by aberrantly activated immune cells. The role of the innate-like T cells, particularly gammadelta T (γδT) cells and MR1-restricted T lymphocytes, is incompletely explored, mainly through animal models, or by use of sur...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 11; p. 572924
Main Authors:	Plužarić, Vera, Štefanić, Mario, Mihalj, Martina, Tolušić Levak, Maja, Muršić, Ivanka, Glavaš-Obrovac, Ljubica, Petrek, Martin, Balogh, Peter, Tokić, Stana
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 03-12-2020
Subjects:	Adult Blood Circulation Cell Differentiation cytokines Cytotoxicity, Immunologic Female gammadelta T lymphocytes Histocompatibility Antigens Class I - metabolism Humans Immunity, Innate Immunology Male Middle Aged Minor Histocompatibility Antigens - metabolism MR1 mucosal associated invariant T cells Mucosal-Associated Invariant T Cells - immunology Promyelocytic Leukemia Zinc Finger Protein - genetics Promyelocytic Leukemia Zinc Finger Protein - metabolism psoriasis Psoriasis - immunology Receptors, Antigen, T-Cell, gamma-delta - metabolism T-Lymphocytes - immunology Th1 Cells - immunology Young Adult gammadelta T lymphocytes cytokines MR1 mucosal associated invariant T cells psoriasis
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