Interaction of (n−3) and (n−6) fatty acids in desaturation and chain elongation of essential fatty acids in cultured glioma cells

Recent research in various biological systems has revived interest in interactions between the (n−6) and (n−3) essential fatty acids. We have utilized cultured glioma cells to show that linolenic acid, 18∶3(n−3), is rapidly desaturated and chain elongated; 20∶5(n−3) is the major product and accumula...

Full description

Saved in:

Bibliographic Details
Published in:	Lipids Vol. 22; no. 9; pp. 613 - 619
Main Authors:	Cook, Harold W., Spence, Matthew W.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer‐Verlag 01-09-1987 Springer
Subjects:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Carbon Radioisotopes Cell Line Fatty Acids, Essential - metabolism Fatty Acids, Nonesterified - metabolism Fundamental and applied biological sciences. Psychology Glioma - metabolism Kinetics Lipids Lysophosphatidylcholines - pharmacology Other biological molecules Structure-Activity Relationship Cell culture Glial cell Regulation(control) Chain length Unsaturated fatty acid Lipids Metabolism Fatty acids
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!