Signaling components of the 1α,25(OH)2D3-dependent Pdia3 receptor complex are required for Wnt5a calcium-dependent signaling

Wnt5a and 1α,25(OH)2D3 are important regulators of endochondral ossification. In osteoblasts and growth plate chondrocytes, 1α,25(OH)2D3 initiates rapid effects via its membrane-associated receptor protein disulfide isomerase A3 (Pdia3) in caveolae, activating phospholipase A2 (PLA2)-activating prot...

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Bibliographic Details

Published in:	Biochimica et biophysica acta. Molecular cell research Vol. 1843; no. 11; pp. 2365 - 2375
Main Authors:	Doroudi, Maryam, Olivares-Navarrete, Rene, Hyzy, Sharon L., Boyan, Barbara D., Schwartz, Zvi
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01-11-2014
Subjects:	1,25-Dihydroxy vitamin D3 Costochondral cartilage growth zone chondrocytes MC3T3-E1 osteoblast-like cells Pdia3 PKC Wnt5a 1,25-Dihydroxy vitamin D3 Pdia3 PKC MC3T3-E1 osteoblast-like cells Wnt5a Costochondral cartilage growth zone chondrocytes
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