Prognosis related to staging systems for chronic lymphocytic leukemia

• Published in: São Paulo medical journal Vol. 118; no. 4; pp. 83 - 88
• Main Authors: de Faria, J R, de Oliveira, J S, Delbone de Faria, R M, Silva, M R, Goihman, S, Yamamoto, M, Kerbauy, J
• Format: Journal Article
• Language: English
• Published: Brazil Associação Paulista de Medicina - APM 06-07-2000; Associação Paulista de Medicina
• Subjects: Adult; Aged; Aged, 80 and over; Analysis of Variance; Chronic Lymphocytic Leukemia; Clinical; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell - mortality; Leukemia, Lymphocytic, Chronic, B-Cell - pathology; Male; MEDICINE, GENERAL & INTERNAL; Middle Aged; Neoplasm Staging; Prognosis; Staging; Survivors; Chronic Lymphocytic Leukemia; Clínica; Prognosis; Staging; Prognóstico; Clinical; Estadiamento; Leucemia linfocítica crônica
• ISSN: 1516-3180; 1806-9460; 1516-3180
• DOI: 10.1590/s1516-31802000000400002

Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients.
To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia.
Evaluation of clinical-staging data.
Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas.
73 patients diagnosed from 1977 to 1994.
Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3
Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female.
The Binet system determined a better prognosis than Rai.