Extended resection in the treatment of colorectal cancer

• Published in: International journal of colorectal disease Vol. 6; no. 3; pp. 161 - 164
• Main Authors: MONTESANI, C, RIBOTTA, G, DE MILITO, R, PRONIO, A, D'AMATO, A, NARILLI, P, JAUS, M
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01-08-1991; Berlin
• Subjects: Adult; Aged; Biological and medical sciences; Colonic Neoplasms - mortality; Colonic Neoplasms - pathology; Colonic Neoplasms - surgery; Female; Follow-Up Studies; Humans; Male; Medical sciences; Middle Aged; Neoplasm Recurrence, Local; Postoperative Period; Prognosis; Rectal Neoplasms - mortality; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Stomach, duodenum, intestine, rectum, anus; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Surgical Procedures, Operative - adverse effects; Surgical Procedures, Operative - methods; Survival Rate; Human; Prognosis; Resection; Toxicity; Surgery; Rectum; Digestive diseases; Tumor; Colon; Survival
• ISSN: 0179-1958; 1432-1262
• DOI: 10.1007/bf00341238

Between 1975 and 1990, 525 patients underwent resection of colorectal cancer in our unit. Of these, 38 had tumour invading adjacent structures and underwent an extended resection. Overall, there were 67 cases treated palliatively. Of these, three were in the group of 38 having an extended resection. When the groups of radical not extended (n = 423) and radical extended resections (n = 35) were compared, respective values for mortality (1.9% vs 0) and morbidity (12.8% vs 11.3%) were not different. Respective local recurrence rates (13% vs 26%) were significantly greater after extended resection. Five-year survival after extended resection was 30%, no different from the general survival rate for standard resections for T2-3 node-positive tumours. Extended resection is thus a safe and important approach for locally advanced tumours.