Synthesis and Superficial Modification "In Situ" of Copper Selenide (Cu 2-x Se) Nanoparticles and Their Antibacterial Activity

• Published in: Nanomaterials (Basel, Switzerland) Vol. 14; no. 13; p. 1151
• Main Authors: Mata-Padilla, José Manuel, Ledón-Smith, José Ángel, Pérez-Alvarez, Marissa, Cadenas-Pliego, Gregorio, Barriga-Castro, Enrique Díaz, Pérez-Camacho, Odilia, Cabello-Alvarado, Christian Javier, Silva, Rodolfo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01-07-2024
• Subjects: Antibacterial activity; Antibacterial agents; Antiinfectives and antibacterials; Antimicrobial agents; antimicrobial susceptibility; Aqueous solutions; Calorimetry; chalcogenides; Chemical reactions; Copper; copper selenide nanoparticles; Copper selenides; Cytology; Differential scanning calorimetry; E coli; Escherichia coli; Fourier transforms; gum arabic; Infrared analysis; Infrared spectroscopy; Metals; Microorganisms; Morphology; Nanoparticles; Nitrates; Outdoor air quality; Particle size; Photovoltaic cells; Proteins; Selenide; Selenium; Solar cells; Staphylococcus aureus; Synthesis; Thermogravimetric analysis; Toxicity; Transmission electron microscopy; X-ray diffraction; Candida albicans; chalcogenides; Escherichia coli; antimicrobial susceptibility; gum arabic; copper selenide nanoparticles; Staphylococcus aureus
• ISSN: 2079-4991; 2079-4991
• DOI: 10.3390/nano14131151

Copper selenide nanoparticles (Cu
Se NPs) have received a lot of attention in recent decades due to their interesting properties and potential applications in various areas such as electronics, health, solar cells, etc. In this study, details of the synthesis and characterization of copper selenide nanoparticles modified with gum arabic (GA) are reported. Also, through transmission electronic microscopy (TEM) analysis, the transformation of the morphology and particle size of copper selenide nanoparticles in aqueous solution was studied. In addition, we present an antimicrobial study with different microorganisms such as
(
),
(
) and
(
). Copper selenide nanoparticles were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry analysis (DSC) and TEM. XRD confirmed the crystal-line structure of the nanoparticles such as cubic berzelanite with a particle size of 6 nm ± 0.5. FTIR and TGA corroborated the surface modification of copper selenide nanoparticles with gum arabic, and DSC suggested a change in the structural phase from cubic to hexagonal. TEM analysis demonstrated that the surface modification of the Cu
Se NPs stabilized the nanostructure of the particles, preventing changes in the morphology and particle size. The antimicrobial susceptibility analysis of copper selenide nanoparticles indicated that they have the ability to inhibit the microbial growth of
,
and
.