LibHip: An open-access hip joint model repository suitable for finite element method simulation
•Open-access hip joint finite element model repository designed for simulation studies.•11 clinically verified subject-specific bilateral models, covering the bones and cartilages in the hip joint area.•Open-access semi-automated modeling workflow using cutting-edge geometry processing tools.•A dire...
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Published in: | Computer methods and programs in biomedicine Vol. 226; p. 107140 |
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Main Authors: | , , , , , , , |
Format: | Journal Article |
Language: | English |
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Elsevier B.V
01-11-2022
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Abstract | •Open-access hip joint finite element model repository designed for simulation studies.•11 clinically verified subject-specific bilateral models, covering the bones and cartilages in the hip joint area.•Open-access semi-automated modeling workflow using cutting-edge geometry processing tools.•A direct geometry processing cartilage reconstruction method using segmented bone models.•Multi-body volume mesh generation, resulting in high-quality discretization, conforming and congruent shared interfaces, and accurate geometries.
Background and objective: population-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation results. Developing large subject-specific population models is challenging and requires extensive manual effort. Thus, the anatomical representations are often subjected to simplification. The discretized geometries do not guarantee conformity in shared interfaces, leading to complications in setting up simulations. Additionally, these models are not openly accessible, challenging reproducibility. Our work provides multiple subject-specific hip joint finite element models and a novel semi-automated modeling workflow.
Methods: we reconstruct 11 healthy subject-specific models, including the sacrum, the paired pelvic bones, the paired proximal femurs, the paired hip joints, the paired sacroiliac joints, and the pubic symphysis. The bones are derived from CT scans, and the cartilages are generated from the bone geometries. We generate the whole complex’s volume mesh with conforming interfaces. Our models are evaluated using both mesh quality metrics and simulation experiments.
Results: the geometry of all the models are inspected by our clinical expert and show high-quality discretization with accurate geometries. The simulations produce smooth stress patterns, and the variance among the subjects highlights the effect of inter-subject variability and asymmetry in the predicted results.
Conclusions: our work is one of the largest model repositories with respect to the number of subjects and regions of interest in the hip joint area. Our detailed research data, including the clinical images, the segmentation label maps, the finite element models, and software tools, are openly accessible on GitHub and the link is provided in Moshfeghifar et al.(2022)[1]. Our aim is to empower clinical researchers to have free access to verified and reproducible models. In future work, we aim to add additional structures to our models. |
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AbstractList | BACKGROUND AND OBJECTIVEpopulation-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation results. Developing large subject-specific population models is challenging and requires extensive manual effort. Thus, the anatomical representations are often subjected to simplification. The discretized geometries do not guarantee conformity in shared interfaces, leading to complications in setting up simulations. Additionally, these models are not openly accessible, challenging reproducibility. Our work provides multiple subject-specific hip joint finite element models and a novel semi-automated modeling workflow. METHODSwe reconstruct 11 healthy subject-specific models, including the sacrum, the paired pelvic bones, the paired proximal femurs, the paired hip joints, the paired sacroiliac joints, and the pubic symphysis. The bones are derived from CT scans, and the cartilages are generated from the bone geometries. We generate the whole complex's volume mesh with conforming interfaces. Our models are evaluated using both mesh quality metrics and simulation experiments. RESULTSthe geometry of all the models are inspected by our clinical expert and show high-quality discretization with accurate geometries. The simulations produce smooth stress patterns, and the variance among the subjects highlights the effect of inter-subject variability and asymmetry in the predicted results. CONCLUSIONSour work is one of the largest model repositories with respect to the number of subjects and regions of interest in the hip joint area. Our detailed research data, including the clinical images, the segmentation label maps, the finite element models, and software tools, are openly accessible on GitHub and the link is provided in Moshfeghifar et al.(2022)[1]. Our aim is to empower clinical researchers to have free access to verified and reproducible models. In future work, we aim to add additional structures to our models. •Open-access hip joint finite element model repository designed for simulation studies.•11 clinically verified subject-specific bilateral models, covering the bones and cartilages in the hip joint area.•Open-access semi-automated modeling workflow using cutting-edge geometry processing tools.•A direct geometry processing cartilage reconstruction method using segmented bone models.•Multi-body volume mesh generation, resulting in high-quality discretization, conforming and congruent shared interfaces, and accurate geometries. Background and objective: population-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation results. Developing large subject-specific population models is challenging and requires extensive manual effort. Thus, the anatomical representations are often subjected to simplification. The discretized geometries do not guarantee conformity in shared interfaces, leading to complications in setting up simulations. Additionally, these models are not openly accessible, challenging reproducibility. Our work provides multiple subject-specific hip joint finite element models and a novel semi-automated modeling workflow. Methods: we reconstruct 11 healthy subject-specific models, including the sacrum, the paired pelvic bones, the paired proximal femurs, the paired hip joints, the paired sacroiliac joints, and the pubic symphysis. The bones are derived from CT scans, and the cartilages are generated from the bone geometries. We generate the whole complex’s volume mesh with conforming interfaces. Our models are evaluated using both mesh quality metrics and simulation experiments. Results: the geometry of all the models are inspected by our clinical expert and show high-quality discretization with accurate geometries. The simulations produce smooth stress patterns, and the variance among the subjects highlights the effect of inter-subject variability and asymmetry in the predicted results. Conclusions: our work is one of the largest model repositories with respect to the number of subjects and regions of interest in the hip joint area. Our detailed research data, including the clinical images, the segmentation label maps, the finite element models, and software tools, are openly accessible on GitHub and the link is provided in Moshfeghifar et al.(2022)[1]. Our aim is to empower clinical researchers to have free access to verified and reproducible models. In future work, we aim to add additional structures to our models. |
ArticleNumber | 107140 |
Author | Schneider, Teseo Moshfeghifar, Faezeh Gholamalizadeh, Torkan Darkner, Sune Ferguson, Zachary Nielsen, Michael Bachmann Panozzo, Daniele Erleben, Kenny |
Author_xml | – sequence: 1 givenname: Faezeh orcidid: 0000-0002-4240-6805 surname: Moshfeghifar fullname: Moshfeghifar, Faezeh email: famo@di.ku.dk organization: Department of Computer Science, University of Copenhagen, Copenhagen 2100, Denmark – sequence: 2 givenname: Torkan surname: Gholamalizadeh fullname: Gholamalizadeh, Torkan organization: Department of Computer Science, University of Copenhagen, Copenhagen 2100, Denmark – sequence: 3 givenname: Zachary surname: Ferguson fullname: Ferguson, Zachary organization: Courant Institute of Mathematical Sciences, New York University, 60 5th Ave, New York, NY 10011, United States – sequence: 4 givenname: Teseo surname: Schneider fullname: Schneider, Teseo organization: Department of Computer Science, University of Victoria, Victoria, BC V8P 5C2, Canada – sequence: 5 givenname: Michael Bachmann surname: Nielsen fullname: Nielsen, Michael Bachmann organization: Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark – sequence: 6 givenname: Daniele surname: Panozzo fullname: Panozzo, Daniele organization: Courant Institute of Mathematical Sciences, New York University, 60 5th Ave, New York, NY 10011, United States – sequence: 7 givenname: Sune surname: Darkner fullname: Darkner, Sune organization: Department of Computer Science, University of Copenhagen, Copenhagen 2100, Denmark – sequence: 8 givenname: Kenny surname: Erleben fullname: Erleben, Kenny organization: Department of Computer Science, University of Copenhagen, Copenhagen 2100, Denmark |
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CitedBy_id | crossref_primary_10_1016_j_cmpb_2022_107140 crossref_primary_10_1016_j_cmpb_2023_107938 crossref_primary_10_1016_j_cmpb_2022_107009 crossref_primary_10_1016_j_jmbbm_2024_106640 |
Cites_doi | 10.1016/j.cmpb.2022.107140 10.1002/jor.22724 10.1016/j.joca.2016.10.023 10.1186/1749-799X-1-6 10.1145/3450626.3459802 10.3233/BME-171685 10.1155/2019/3973170 10.1136/jamia.1996.96236280 10.1007/s00776-010-1511-z 10.1371/journal.pone.0146452 10.1016/j.joca.2013.06.008 10.1080/10255849908907983 10.1016/j.jbiomech.2011.06.011 10.1016/j.cmpb.2009.01.004 10.1145/3197517.3201353 10.1145/3386569.3392385 10.1007/s00330-015-3964-0 10.1145/2010324.1964973 10.1145/3134472.3134497 10.1016/j.cmpb.2021.106273 10.1016/j.medengphy.2006.08.010 10.1016/j.jbiomech.2010.01.010 10.36076/ppj.2014/17/43 10.1145/37402.37420 10.1056/NEJMoa0800996 10.1016/j.cmpb.2020.105714 10.1007/s12178-013-9174-y 10.1007/s10278-013-9622-7 10.1007/s00776-004-0866-4 10.1111/os.12315 10.1016/j.aott.2017.02.008 10.1115/1.2953472 10.1002/jor.22040 10.1115/1.4023386 10.1109/TVCG.2013.97 10.1002/jor.22245 10.1016/j.media.2010.01.006 10.1007/978-3-319-10404-1_65 10.1002/cnm.2530 10.1007/978-3-031-09327-2_11 10.1145/3272127.3275067 10.1016/j.cmpb.2022.107009 10.1016/j.medengphy.2015.11.021 10.1145/3508372 10.1016/j.apm.2019.07.055 10.1016/S1350-4533(02)00113-3 10.1016/j.medengphy.2008.11.015 10.1115/1.4005694 10.1016/j.joca.2013.11.003 10.1002/jor.20747 10.1097/CORR.0000000000000755 10.1145/3386569.3392425 10.1016/j.joca.2006.10.005 10.1007/978-3-031-16760-7_15 10.1002/(SICI)1097-0207(19971115)40:21<3979::AID-NME251>3.0.CO;2-9 10.1007/978-3-319-10404-1_68 10.1038/sdata.2016.18 |
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Keywords | Population-based finite element analysis Multi-body meshing Hip joint repository |
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Snippet | •Open-access hip joint finite element model repository designed for simulation studies.•11 clinically verified subject-specific bilateral models, covering the... BACKGROUND AND OBJECTIVEpopulation-based finite element analysis of hip joints allows us to understand the effect of inter-subject variability on simulation... |
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Title | LibHip: An open-access hip joint model repository suitable for finite element method simulation |
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