k-t BLAST and SENSE accelerated time-resolved three-dimensional phase contrast MRI in an intracranial aneurysm

• Published in: Magma (New York, N.Y.) Vol. 26; no. 3; pp. 261 - 270
• Main Authors: van Ooij, Pim, Guédon, Annetje, Marquering, Henk A., Schneiders, Joppe J., Majoie, Charles B., van Bavel, Ed, Nederveen, Aart J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01-06-2013
• Subjects: Biomedical Engineering and Bioengineering; Blood Flow Velocity; Cerebral Arteries - pathology; Cerebral Arteries - physiopathology; Cerebrovascular Circulation; Computer Appl. in Life Sciences; Computer Simulation; Health Informatics; Humans; Image Interpretation, Computer-Assisted - methods; Imaging; Intracranial Aneurysm - pathology; Intracranial Aneurysm - physiopathology; Magnetic Resonance Angiography - instrumentation; Magnetic Resonance Angiography - methods; Medicine; Medicine & Public Health; Models, Cardiovascular; Phantoms, Imaging; Radiology; Reproducibility of Results; Research Article; Sensitivity and Specificity; Solid State Physics; Phantom; Phase Contrast MRI; -; BLAST; Intracranial aneurysm
• ISSN: 0968-5243; 1352-8661
• DOI: 10.1007/s10334-012-0336-5

Objective
The objective of this study was to investigate the performance of
k
-
t
BLAST (Broad-use Linear Acquisition Speed-up Technique) accelerated time-resolved 3D PC-MRI compared to SENSE (SENSitivity Encoding) acceleration in an in vitro and in vivo intracranial aneurysm.
Materials and methods
Non-accelerated, SENSE and
k
-
t
BLAST accelerated time-resolved 3D PC-MRI measurements were performed in vivo and in vitro. We analysed the consequences of various temporal resolutions in vitro.
Results
Both in vitro and in vivo measurements showed that the main effect of
k
-
t
BLAST was underestimation of velocity during systole. In the phantom, temporal blurring decreased with increasing temporal resolution. Quantification of the differences between the non-accelerated and accelerated measurements confirmed that in systole SENSE performed better than
k
-
t
BLAST in terms of mean velocity magnitude. In both in vitro and in vivo measurements,
k
-
t
BLAST had higher SNR compared to SENSE. Qualitative comparison between measurements showed good similarity.
Conclusion
Comparison with SENSE revealed temporal blurring effects in
k
-
t
BLAST accelerated measurements.