Comparison and integration of first trimester fetal nuchal translucency and second trimester maternal serum screening for fetal Down syndrome

Background It is uncertain whether first trimester nuchal translucency (NT) is more effective than the well‐established second trimester serum screening for fetal Down syndrome or whether their combination works best. We report data from a large multicentre non‐interventional trial in which all subj...

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Bibliographic Details
Published in:	Prenatal diagnosis Vol. 22; no. 8; pp. 730 - 735
Main Authors:	Hang Lam, Yung, Peng Lee, Chin, Yuen Sin, Sai, Tang, Rebecca, Soo Wong, Hong, Fun Wong, Sai, Yee Tak Fong, Danial, Hoi Yin Tang, Mary, Hai Nin Woo, Hennie
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-08-2002 Wiley
Subjects:	alpha-Fetoproteins - analysis Amniocentesis Biological and medical sciences Biomarkers - blood Chorionic Gonadotropin - blood Chromosome aberrations Down syndrome Down Syndrome - blood Down Syndrome - diagnosis Down Syndrome - diagnostic imaging False Positive Reactions Gestational Age Gynecology. Andrology. Obstetrics Hydrops Fetalis - diagnostic imaging Management. Prenatal diagnosis Maternal Age Medical genetics Medical sciences Neck - diagnostic imaging Neck - embryology nuchal translucency Pregnancy, High-Risk Pregnancy. Fetus. Placenta Prenatal Diagnosis Risk Factors ROC Curve screening serum screening Ultrasonography, Prenatal ultrasound Chromosomal aberration Sonography Second trimester Human Integration Multicenter study Aneuploidy First trimester Down syndrome Medical screening Congenital disease Blood plasma Prenatal Translucence Mother Echography Female Fetus Neck Diagnosis Comparative study
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