Therapeutic liver repopulation in a mouse model of hypercholesterolemia

Liver repopulation constitutes an attractive approach for the treatment of liver disorders or of diseases requiring abundant secretion of an active protein. We have described previously a model of selective repopulation of a normal liver by Fas/CD95-resistant hepatocytes, in which we achieved up to...

Full description

Saved in:

Bibliographic Details
Published in:	Human molecular genetics Vol. 9; no. 11; pp. 1597 - 1602
Main Authors:	MITCHELL, C, MIGNON, A, GUIDOTTI, J. E, BESNARD, S, FABRE, M, DUVERGER, N, PARLIER, D, TEDGUI, A, KAHN, A, GILGENKRANTZ, H
Format:	Journal Article
Language:	English
Published:	Oxford Oxford University Press 01-07-2000 Oxford Publishing Limited (England)
Subjects:	Animals Apolipoproteins E - blood Apolipoproteins E - genetics Apolipoproteins E - metabolism Arteriosclerosis - pathology Biological and medical sciences CD95 antigen Cell Transplantation Cholesterol - blood Disease Models, Animal Disorders of blood lipids. Hyperlipoproteinemia Fas ligand Humans hypercholesterolemia Hypercholesterolemia - therapy Lipoproteins - blood Liver - cytology Liver - metabolism Liver - pathology Medical sciences Metabolic diseases Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Mutation Proto-Oncogene Proteins c-bcl-2 - metabolism Animal model Liver Rodentia Transgenic animal Metabolic diseases Lipids Hyperlipoproteinemia Gene expression Cholesterol Vertebrata Mammalia Hypercholesterolemia Hepatocyte Mouse Apolipoprotein E Atherosclerosis Apoptosis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!