Protein lipid modifications in signaling and subcellular targeting

Protein lipid modifications in signaling and subcellular targeting

Classically perceived as means for recruiting proteins to the membranes, protein lipid modifications are known today to play diverse roles in subcellular targeting, protein–protein interactions and signaling. This review focuses on three protein lipid modifications: prenylation, S-acylation and N-my...

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Bibliographic Details
Published in:Current opinion in plant biology Vol. 12; no. 6; pp. 714 - 720
Main Authors: Sorek, Nadav, Bloch, Daria, Yalovsky, Shaul
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-12-2009
[Oxford, UK]: Pergamon: Elsevier Science
Subjects:
Acylation
biochemical pathways
cell membranes
lipids
Lipoylation
literature reviews
N-myristoylation
Plant Proteins - chemistry
plants
prenylation
protein composition
protein metabolism
Protein Prenylation
protein structure
protein transport
protein-protein interactions
Signal Transduction
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Summary:Classically perceived as means for recruiting proteins to the membranes, protein lipid modifications are known today to play diverse roles in subcellular targeting, protein–protein interactions and signaling. This review focuses on three protein lipid modifications: prenylation, S-acylation and N-myristoylation and attempts to provide an up-to-date view of their function by focusing on several model proteins.
Bibliography:http://dx.doi.org/10.1016/j.pbi.2009.09.003
ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-2
ISSN:1369-5266
1879-0356
DOI:10.1016/j.pbi.2009.09.003