Bone Marrow-Derived Mesenchymal Stem Cells Reverse Radiotherapy-Induced Premature Ovarian Failure: Emphasis on Signal Integration of TGF-β, Wnt/β-Catenin and Hippo Pathways

Radiotherapy is an indispensable cancer treatment approach. However, it is associated with hazardous consequences on multiple organs characterized by insidious worsening severity over time. This study aimed to examine the potential therapeutic effects of bone marrow mesenchymal stem cells (BM-MSCs)...

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Bibliographic Details
Published in:	Stem cell reviews and reports Vol. 17; no. 4; p. 1429
Main Authors:	El-Derany, Marwa O, Said, Riham S, El-Demerdash, Ebtehal
Format:	Journal Article
Language:	English
Published:	United States 01-08-2021
Subjects:	Animals beta Catenin - metabolism Bone Marrow - metabolism Female Hippo Signaling Pathway Mesenchymal Stem Cells - metabolism Primary Ovarian Insufficiency - etiology Primary Ovarian Insufficiency - therapy Radiation Injuries, Experimental Radiotherapy - adverse effects Rats Transforming Growth Factor beta - metabolism Wnt Signaling Pathway miRNAs Hippo signaling pathway BM-MSCs POF Wnt/β-catenin
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