Clinico-pathological and molecular characterization of diffuse midline gliomas: is there a prognostic significance?

Purpose H3K27M mutant diffuse midline gliomas (DMGs) are considered grade IV irrespective of histological features and have dismal prognosis. We evaluated clinico-pathologic, radiological, and molecular characteristics of DMGs across all ages. Methods One twenty-six DMGs were identified over 10 year...

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Bibliographic Details
Published in:	Neurological sciences Vol. 42; no. 3; pp. 925 - 934
Main Authors:	Manjunath, Niveditha, Jha, Prerana, Singh, Jyotsna, Raheja, Amol, Kaur, Kavneet, Suri, Ashish, Garg, Ajay, Sharma, Mehar Chand, Sarkar, Chitra, Mohan, Madan, Mani, Kalaivani, Suri, Vaishali
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-03-2021 Springer Nature B.V
Subjects:	Adult Brain Neoplasms - genetics Brain stem Child Demography Glioma Glioma - genetics Histones - genetics Humans Immunohistochemistry Isocitrate Dehydrogenase - genetics Medical prognosis Medicine Medicine & Public Health Mutants Mutation Neurology Neuroradiology Neurosciences Neurosurgery Original Article Pediatrics Prognosis Psychiatry Survival Survival analysis Thalamus Survival analysis Adults Diffuse midline gliomas H3K27M mutation Overall survival Pediatric
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