The significance of cutaneous metastasis from visceral tumors diagnosed by fine-needle aspiration biopsy

• Published in: Diagnostic cytopathology Vol. 3; no. 1; p. 24
• Main Authors: Pak, H Y, Foster, B A, Yokota, S B
• Format: Journal Article
• Language: English
• Published: United States 01-03-1987
• Subjects: Adolescent; Adult; Aged; Biopsy, Needle; Child; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Melanoma - secondary; Middle Aged; Oropharyngeal Neoplasms; Skin Neoplasms - diagnosis; Skin Neoplasms - secondary
• ISSN: 8755-1039
• DOI: 10.1002/dc.2840030106

Cutaneous metastases from various visceral organs were studied in 43 patients. The morphologic diagnosis in each case was established by fine-needle aspiration cytodiagnosis. There were 28 males and 15 females, with median ages of 62 and 61 yr, respectively. The most common primary tumor in men was carcinoma of the lung (35%), followed by malignant melanoma (21%) and carcinoma of the oropharynx (14%). In women, the most frequent primary cancers were carcinoma of the colon (59%) and lung (20%). Metastatic cutaneous lesions were more frequent in the back (23%), upper extremities (21%), and scalp (12%). Median survival from onset of cutaneous metastasis was shortest in primary lung cancer at 3 mo followed by colon at 5 mo and oropharynx at 5.5 mo. Our study confirms that cutaneous metastasis represents a terminal manifestation of the disease due to either hematogenous or lymphatic spread. This study also reiterates the clinical usefulness of needle aspiration biopsy as an alternative diagnostic tool in establishing the presence of cutaneous metastasis.