Asymmetric total syntheses of panaxytriol and panaxydol, potent antitumor agents from Panax ginseng

Asymmetric total syntheses of panaxytriol and panaxydol, potent antitumor agents from Panax ginseng

A stereoselective syntheses of panaxytriol 1 and panaxydol 2 from d-arabinose using base induced double elimination of 4,5- O-isopropylidene propargyl chloride as a key step is described. Graphic

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Bibliographic Details
Published in:Tetrahedron Vol. 58; no. 24; pp. 4955 - 4961
Main Authors: Yadav, J.S, Maiti, Arup
Format: Journal Article
Language:English
Published: Elsevier Ltd 10-06-2002
Subjects:
asymmetric total synthesis
Panax ginseng
panaxytriol
Panax ginseng
panaxytriol
asymmetric total synthesis
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Description
Summary:A stereoselective syntheses of panaxytriol 1 and panaxydol 2 from d-arabinose using base induced double elimination of 4,5- O-isopropylidene propargyl chloride as a key step is described. Graphic
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(02)00423-4