Profiling Auspicious Butyrylcholinesterase Inhibitory Activity of Two Herbal Molecules: Hyperforin and Hyuganin C

Cholinergic therapy based on cholinesterase (ChE) inhibitory drugs is the mainstay for the treatment of Alzheimer's disease. Therefore, an extensive research has been continuing for the discovery of drug candidates as inhibitors of acetyl‐ and butyrylcholinesterase. In this study, two natural m...

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Bibliographic Details
Published in:	Chemistry & biodiversity Vol. 16; no. 5; pp. e1900017 - n/a
Main Authors:	Orhan, Ilkay Erdogan, Senol Deniz, F. Sezer, Trædal‐Henden, Steinar, Cerón‐Carrasco, José P., den Haan, Helena, Peña‐García, Jorge, Pérez‐Sánchez, Horacio, Emerce, Esra, Skalicka‐Wozniak, Krystyna
Format:	Journal Article
Language:	English
Published:	Switzerland Wiley Subscription Services, Inc 01-05-2019
Subjects:	Acetylcholinesterase - chemistry Acetylcholinesterase - metabolism Alzheimer's disease Apiaceae - chemistry Binding Sites butyrylcholinesterase Butyrylcholinesterase - chemistry Butyrylcholinesterase - metabolism Catalysis Catalytic Domain Cholinergics Cholinesterase Cholinesterase Inhibitors - chemistry coumarin Coumarins - chemistry Coumarins - isolation & purification Drug development enzyme inhibition Galantamine Hepatotoxicity Hydrophobicity Inhibitors Medical treatment Molecular docking Molecular Docking Simulation natural products Neurodegenerative diseases Phloroglucinol - analogs & derivatives Phloroglucinol - chemistry Plant Extracts - chemistry Quantitative Structure-Activity Relationship Residues Terpenes - chemistry Therapy Thermodynamics natural products butyrylcholinesterase molecular docking enzyme inhibition coumarin
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