Efficient synthesis of optically active 1-(2-carboxymethyl-6-ethylphenyl)- 1H-pyrrole-2-carboxylic acid: a novel atropisomeric 1-arylpyrrole derivative

An efficient synthesis and resolution of (±)-1-(2-carboxymethyl-6-ethylphenyl)- 1H-pyrrole-2-carboxylic acid has been developed for the preparation of novel optically active atropisomers. The ee values were measured by a 1H NMR spectroscopic method using quinidine as the chiral complexing agent. Abs...

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Bibliographic Details

Published in:	Tetrahedron: asymmetry Vol. 20; no. 1; pp. 98 - 103
Main Authors:	Faigl, Ferenc, Vas-Feldhoffer, Bernadett, Kubinyi, Miklós, Pál, Krisztina, Tárkányi, Gábor, Czugler, Mátyás
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 01-01-2009
Online Access:	Get full text
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