One step closer to sparing total blood loss and transfusion rate in total knee arthroplasty: a meta-analysis of different methods of tranexamic acid administration

Background Tranexamic acid (TXA) in orthopedics has recently been gaining favor due to its efficacy and ease of use, both in intravenous (IV) and intraarticular (IA) usage. However, because of safety concerns with IV administration, there has been a growing interest in the IA use of TXA to prevent b...

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Bibliographic Details
Published in:	Archives of orthopaedic and trauma surgery Vol. 135; no. 4; pp. 573 - 588
Main Authors:	Shemshaki, Hamidreza, Nourian, Sayed Mohammad Amin, Nourian, Niloofaralsadat, Dehghani, Masoudhatef, Mokhtari, Masoud, Mazoochian, Farhad
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01-04-2015 Springer Nature B.V
Subjects:	Antifibrinolytic agents Antifibrinolytic Agents - administration & dosage Arthroplasty, Replacement, Knee - adverse effects Blood Loss, Surgical - prevention & control Blood Loss, Surgical - statistics & numerical data Blood Transfusion - utilization Health risk assessment Humans Infusions, Intravenous Joint surgery Knee Arthroplasty Medicine Medicine & Public Health Meta-analysis Orthopedics Systematic review Thromboembolism Tranexamic Acid - administration & dosage Tranexamic acid Total knee arthroplasty Intraarticular Intravenous Meta-analysis
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