Analysis of nine cases of oral foreign body granuloma related to biomaterials

• Published in: Journal of biosciences Vol. 44; no. 4; pp. 1 - 8
• Main Authors: Rolim, Larissa Santos Amaral, da Silva Barros, Caio César, Pinheiro, Juliana Campos, de Oliveira, Patrícia Teixeira, de Souza, Lélia Batista, de Andrade Santos, Pedro Paulo
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01-09-2019; Springer Nature B.V
• Subjects: Accidents; Adolescent; Adult; Biomaterials; Biomedical and Life Sciences; Biomedical materials; Biomedicine; Cell Biology; Dental materials; Dental Materials - adverse effects; Dental Restoration, Permanent - adverse effects; Female; Foreign bodies; Foreign Bodies - chemically induced; Foreign Bodies - diagnostic imaging; Foreign Bodies - pathology; Granuloma; Granuloma, Foreign-Body - chemically induced; Granuloma, Foreign-Body - diagnostic imaging; Granuloma, Foreign-Body - pathology; Granulomas; Histopathology; Humans; Inflammation - chemically induced; Inflammation - diagnostic imaging; Inflammation - pathology; Life Sciences; Literature reviews; Macrophages; Macrophages - drug effects; Macrophages - pathology; Male; Microbiology; Middle Aged; Plant Sciences; Procedures; Young Adult; Zoology; endodontic filler; foreign body granuloma; foreign body; Cosmetic filler
• ISSN: 0250-5991; 0973-7138
• DOI: 10.1007/s12038-019-9898-y

Foreign bodies can penetrate the interior of soft and, sometimes, hard, tissues in various ways, including through open wounds, lacerations and traumatic accidents. However over the years, evidence of links between the use of dental materials and lately, significant involvement of aesthetic filler materials as foreign bodies in the oral and perioral region have been reported. Foreign body granulomas (FBGs) may develop from this exogenous material, histopathologically characterized by the presence of chronic inflammation and a high amount of macrophages. This study presents nine FBG cases affecting the oral and perioral regions, and carries out a literature review on the main clinical, histopathological and material characteristics used in dental and dermatological procedures related to the appearance of this type of granuloma.