Time trend tendency (1988–2014 years) of organochlorine pesticide levels in the adipose tissue of Veracruz inhabitants

• Published in: Environmental monitoring and assessment Vol. 190; no. 4; pp. 206 - 10
• Main Authors: Calderón-Garcidueñas, Ana Laura, Waliszewski, Stefan M., Ruiz-Ramos, Rubén, del Carmen Martinez-Valenzuela, María
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01-04-2018; Springer Nature B.V
• Subjects: Adipose tissue; Adipose Tissue - chemistry; Adult; Atmospheric Protection/Air Quality Control/Air Pollution; Bioaccumulation; Body fat; Chlorine compounds; Computational fluid dynamics; DDD; DDE; DDT; Decontamination; Dengue fever; Earth and Environmental Science; Ecology; Ecotoxicology; Environment; Environmental Exposure - analysis; Environmental Management; Environmental monitoring; Environmental Pollutants - analysis; Environmental science; Female; Fluids; Food contamination; Forensic engineering; Forensic science; Forensic Toxicology; Hexachlorobenzene; Human diseases; Humans; Hydrocarbons, Chlorinated - analysis; Inhabitants; Lindane; Lipid metabolism; Lipids; Lipophilic; Malaria; Mexico; Monitoring/Environmental Analysis; Nitrous oxide; Organic compounds; Organochlorine pesticides; Particulate matter; PCB; Pesticide Residues - analysis; Pesticides; Polychlorinated biphenyls; Surveying; Suspended particulate matter; Time Factors; Tissue; Vapors; Vector-borne diseases; Vectors; Mexico; Veracruz, Mexico; Adipose tissue; Organochlorine pesticides; Time tendency
• ISSN: 0167-6369; 1573-2959
• DOI: 10.1007/s10661-018-6581-y

The population that lives in areas where organochlorine pesticides were spread in the past is still exposed to them through contaminated food, particulate matter, and vapors. Due to their lipophilic properties and resistance to metabolic reactions, they accumulate in tissues and fluids rich in lipids. The aim of the study was to monitor the concentrations of organochlorine pesticides in forensic adipose tissue samples of adult inhabitants of Veracruz City, Mexico, and compare their time trend levels from 1988 to 2014. During the study, hexachlorobenzene (HCB); lindane; β-hexachorocyclohexane; p,p′-dichlorodiphenyldichloroethylene (pp′DDE); p,p′-dichlorodiphenyldichloroethane (p,p′-DDT); and o,p′-dichlorodiphenyldichloroethane (o,p′-DDT) were determined. Our survey was divided into two periods: first, from the years 1988 to 1999, during which DDT was allowed to fight malaria and dengue vectors and the second from the years 2001 to 2014, after the DDT ban. A total of 1435 samples were analyzed. There were substantial differences in the forecasted time trend values of p,p′-DDE and p,p′-DDT in human adipose tissue samples in the two different periods. During the first period, p,p′-DDE decrease time trend was 1.198 mg/kg on lipid base per year; for the second one, decrease was 0.128 mg/kg on lipid base per year. p,p′-DDT decreased 0.507 mg/kg on lipid base during the first period and 0.039 mg/kg on lipid base for the second. The different concentrations may be explained by the cessation of fresh exposure after the first period and a more equilibrated decontamination tendency during the second period. This model was useful to show the decrease in the concentration of pesticides in human adipose tissue samples.