A new polyketide from the bark of Hypericum roeperianum Schimp. (Hypericaceae)

The isolation and spectroscopic data of a hitherto undescribed polyketide (1) from Hypericum roeperianum Schimp. (Hypericaceae) together with six known compounds (2-7) is herein reported. The structure elucidation is based on extensive 1D- and 2D-NMR, infrared, UV and MS experiments. The structures...

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Bibliographic Details
Published in:	Natural product research Vol. 35; no. 14; pp. 2381 - 2387
Main Authors:	Damen, François, Demgne, Olive Monique F., Bitchagno, Gabin Thierry M., Celik, Ilhami, Mpetga, James D. Simo, Tankeo, Simplice Beaudelaire, Opatz, Till, Kuete, Victor, Tane, Pierre
Format:	Journal Article
Language:	English
Published:	Abingdon Taylor & Francis 01-07-2021 Taylor & Francis Ltd
Subjects:	antibacterial Bark Hypericaceae Hypericum Hypericum roeperianum MDR Multidrug resistance NMR Nuclear magnetic resonance polyketide Spectroscopy
Online Access:	Get full text
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Summary:	The isolation and spectroscopic data of a hitherto undescribed polyketide (1) from Hypericum roeperianum Schimp. (Hypericaceae) together with six known compounds (2-7) is herein reported. The structure elucidation is based on extensive 1D- and 2D-NMR, infrared, UV and MS experiments. The structures of the known compounds were confirmed by comparison of their spectroscopic data with those of similar reported compounds in the literature. Some of the isolated compounds had a significant activity against a panel of multidrug-resistant bacterial strains. Supplemental data for this article can be accessed at https://doi.org/10.1080/14786419.2019.1677655 .
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1478-6419 1478-6427
DOI:	10.1080/14786419.2019.1677655