Brain derived neurotrophic factor Val66Met polymorphism and psychotic symptoms in Alzheimer's disease

Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative disorder with a high prevalence. Since behavioral disturbances, such as psychotic symptoms, represent a key feature of AD, genes related to dopamine, serotonin and brain derived neurotrophic factor (BDNF), are considered...

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Bibliographic Details
Published in:	Progress in neuro-psychopharmacology & biological psychiatry Vol. 35; no. 2; pp. 356 - 362
Main Authors:	Pivac, Nela, Nikolac, Matea, Nedic, Gordana, Mustapic, Maja, Borovecki, Fran, Hajnsek, Sanja, Presecki, Paola, Pavlovic, Mladen, Mimica, Ninoslav, Muck Seler, Dorotea
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 30-03-2011
Subjects:	Age Factors Alzheimer Disease - epidemiology Alzheimer Disease - genetics Alzheimer Disease - physiopathology Alzheimer Disease - psychology Alzheimer's disease Amino Acid Substitution Brain derived neurotrophic factor Val66Met Brain-Derived Neurotrophic Factor - genetics Brain-Derived Neurotrophic Factor - physiology Croatia Disease Progression Female Gene Frequency Genetic Predisposition to Disease Genotype Humans Male Male and female subjects Onset of disease Polymorphism, Single Nucleotide Psychotic Disorders - genetics Psychotic Disorders - physiopathology Psychotic symptoms Schizophrenia - genetics Schizophrenia - physiopathology Sex Factors Time Factors Croatia Val Male and female subjects AD ANOVA BDNF Onset of disease MMSE Psychotic symptoms HWE Brain derived neurotrophic factor Val66Met Met Alzheimer's disease
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