Chronic exposure to fungicide propamocarb induces bile acid metabolic disorder and increases trimethylamine in C57BL/6J mice

Propamocarb (PM) is a widely used fungicide that affects lipid biosynthesis in fungi. In this study, we explored the effects of PM on mouse metabolism and gut microbiota-related pathways by exposing C57BL/6J mice to 1, 3, and 10 mg/L PM through drinking water for a duration of 10 weeks. We found tha...

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Bibliographic Details
Published in:	The Science of the total environment Vol. 642; pp. 341 - 348
Main Authors:	Wu, Sisheng, Luo, Ting, Wang, Siyu, Zhou, Jicong, Ni, Yingchun, Fu, Zhengwei, Jin, Yuanxiang
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 15-11-2018
Subjects:	Animals Bile acids Bile Acids and Salts - metabolism Carbamates - toxicity Energy metabolism Gut microbiota Liver Metabolic Diseases - chemically induced Methylamines - metabolism Mice Mice, Inbred C57BL Propamocarb Toxicity Tests Trimethylamine Gut microbiota Energy metabolism Bile acids Trimethylamine Propamocarb
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