Rapid progression to high‐grade dysplasia in barrett's esophagus after liver transplantation

There is an increased incidence of malignancies in transplant recipients. Accelerated progression from a premalignant lesion to carcinoma has been reported in transplant recipients with skin cancer and colon cancer. Whereas Barrett's esophagus is a common premalignant condition in the normal po...

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Bibliographic Details
Published in:	Liver Transplantation and Surgery Vol. 5; no. 4; pp. 332 - 333
Main Authors:	Trotter, James F., Brazer, Scott R.
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA W.B. Saunders 01-07-1999
Subjects:	Adult Barrett Esophagus - pathology Barrett Esophagus - physiopathology Disease Progression Esophageal Neoplasms - pathology Esophageal Neoplasms - physiopathology Hepatitis C - surgery Humans Immunosuppressive Agents - therapeutic use Liver Cirrhosis - surgery Liver Cirrhosis - virology Liver Transplantation - adverse effects Male Metaplasia Precancerous Conditions - pathology Precancerous Conditions - physiopathology
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Summary:	There is an increased incidence of malignancies in transplant recipients. Accelerated progression from a premalignant lesion to carcinoma has been reported in transplant recipients with skin cancer and colon cancer. Whereas Barrett's esophagus is a common premalignant condition in the normal population, rapid progression to severe dysplasia or carcinoma has not been widely reported in transplant recipients. We report on a liver transplant recipient who developed rapid progression from Barrett's esophagus without dysplasia to high‐grade dysplasia within 9 months after transplantation.
ISSN:	1074-3022 1527-6473
DOI:	10.1002/lt.500050405