An unusual presentation of extramedullary plasmacytoma in testis and review of the literature

• Published in: Medical oncology (Northwood, London, England) Vol. 27; no. 4; pp. 1378 - 1380
• Main Authors: Turk, H. Mehmet, Komurcu, Seref, Ozet, Ahmet, Kuzhan, Okan, Günhan, Ömer
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01-12-2010; Springer Nature B.V
• Subjects: Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Diagnosis, Differential; Hematology; Humans; Internal Medicine; Male; Medicine; Medicine & Public Health; Multiple Myeloma - complications; Multiple Myeloma - diagnosis; Multiple Myeloma - therapy; Oncology; Orchiectomy; Original Paper; Pathology; Plasmacytoma - complications; Plasmacytoma - diagnosis; Plasmacytoma - therapy; Prognosis; Radiotherapy Dosage; Testicular Neoplasms - complications; Testicular Neoplasms - diagnosis; Testicular Neoplasms - therapy; Testis; Plasmacytoma; Extramedullary plasmacytoma; Multiple myeloma
• ISSN: 1357-0560; 1559-131X
• DOI: 10.1007/s12032-009-9390-x

Extramedullary plasmacytoma is a rare plasma cell neoplasm, and it is extremely uncommon in the testicles. We report a 73-year-old man with multiple myeloma presented with testicular plasmacytoma. He complained of left leg pain and scrotal swelling. Ultrasonography revealed testicular masses. Pathologic examination of the orchiectomy specimen showed plasmocytoma with kappa expression. Multiple lytic bone lesions were seen in bone survey scans, serum immunoelectrophoresis and bone marrow aspiration aided to the diagnosis of multiple myeloma. He received chemotherapy, melphalan and prednisolone, and palliative radiotherapy. He succumbed to disease after 8 months.