Formation of Monozygotic Twins: When Does it Occur?

An individual embryo from day 15 of gestation in the rhesus monkey showed partial separation of the cranial end of the embryonic shield into two separate cell masses with separate amnions but with a common yolk sac. Although what the fate of this conceptus might have been is not known, it demonstrat...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 23; no. 2-3; pp. 236 - 238
Main Author:	Enders, A.C.
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01-02-2002 Elsevier
Subjects:	Animals Biological and medical sciences Embryo Implantation - physiology Female Fundamental and applied biological sciences. Psychology Gestational Age Macaca mulatta - embryology Mother. Fetoplacental unit. Mammary gland. Milk Pregnancy Pregnancy. Parturition. Lactation Twins, Monozygotic Vertebrates: reproduction Pregnancy Vertebrata Embryo Mammalia Monkey Primates Female Monozygotic twin
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Summary:	An individual embryo from day 15 of gestation in the rhesus monkey showed partial separation of the cranial end of the embryonic shield into two separate cell masses with separate amnions but with a common yolk sac. Although what the fate of this conceptus might have been is not known, it demonstrates that the physical features of implantation in this primate are permissive of relatively late division of the epiblast, which suggests that monozygotic twinning may occur as late as the embryonic shield stage just prior to primitive streak formation.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0143-4004 1532-3102
DOI:	10.1053/plac.2001.0755