Human kininogens interact with M protein, a bacterial surface protein and virulence determinant

Streptococcus pyogenes, the most significant streptococcal species in clinical medicine, expresses surface proteins with affinity for several human plasma proteins. Here we report that kininogens, the precursors to the vasoactive kinins, bind to the surface of S. pyogenes. M protein, a surface molec...

Full description

Saved in:

Bibliographic Details
Published in:	Biochemical journal Vol. 305 ( Pt 1); no. 1; pp. 173 - 180
Main Authors:	Ben Nasr, A B, Herwald, H, Müller-Esterl, W, Björck, L
Format:	Journal Article
Language:	English
Published:	England 01-01-1995
Subjects:	Amino Acid Sequence Antibodies - metabolism Antibodies - pharmacology Antigens, Bacterial Bacterial Outer Membrane Proteins Bacterial Proteins - metabolism Binding Sites Carrier Proteins Enzyme-Linked Immunosorbent Assay Fibrinogen - metabolism Humans Kininogens - metabolism Molecular Sequence Data Peptide Mapping Protein Binding Streptococcus pyogenes - metabolism Streptococcus pyogenes - pathogenicity Virulence
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!