Is It Possible to Save the Deep Brain Stimulation Hardware when Presenting with Wound Dehiscence or Hardware Infection?

• Published in: Stereotactic and functional neurosurgery Vol. 99; no. 6; p. 496
• Main Authors: Ginalis, Elizabeth E, Hargreaves, Eric L, Caputo, Deborah L, Danish, Shabbar F
• Format: Journal Article
• Language: English
• Published: Switzerland 2021
• Subjects: Deep Brain Stimulation - adverse effects; Electrodes, Implanted - adverse effects; Humans; Postoperative Complications - etiology; Quality of Life; Reoperation; Retrospective Studies; Functional neurosurgery; Deep brain stimulation; Surgical wound infection; Essential tremor; Movement disorder surgery; Movement disorders; Parkinson’s disease
• ISSN: 1423-0372
• DOI: 10.1159/000517299

Deep brain stimulation (DBS) hardware complications have been traditionally managed by removal of the entire system. Explantation of the system results in prolonged interruption to the patient's care and potential challenges when considering reimplantation of the cranial leads. The purpose of this study was to understand whether complete explantation can be avoided for patients initially presenting with wound dehiscence and/or infection of hardware.
We performed a retrospective study that included 30 cases of wound dehiscence or infection involving the DBS system. Patients underwent reoperation without explantation of the DBS system, with partial explanation, or with complete explantation as initial management of the complication.
A total of 17/30 cases were managed with hardware-sparing wound revisions. The majority presented with wound dehiscence (94%), with the scalp (n = 9) as the most common location. This was successful in 76.5% of patients (n = 13). Over 11/30 patients were managed with partial explantation. The complication was located at the generator (91%) or at the scalp (9%). Partial explantation was successful in 64% of patients (n = 7). In cases that underwent a lead-sparing approach, 33% of patients ultimately required removal of the intracranial lead, and 2/30 cases of hardware infection were managed initially with total explantation.
Wound dehiscence can be successfully managed without complete removal of the DBS system in most cases. In cases of infection, removing the involved component(s) and sparing the intracranial leads may be considered. Wound revision without removal of the entire DBS system is safe and can improve quality of life by preventing or shortening the withdrawal of DBS treatment.