Sertoli Cell Tumor in Androgen Insensitivity Syndrome—A Case Report

• Published in: Gynecologic oncology Vol. 75; no. 3; pp. 480 - 483
• Main Authors: Wysocka, Barbara, Serkies, Krystyna, Debniak, Jarosław, Jassem, Jacek, Limon, Janusz
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 01-12-1999; Elsevier
• Subjects: Adult; Androgen-Insensitivity Syndrome - pathology; Androgen-Insensitivity Syndrome - therapy; Biological and medical sciences; Female; Gynecology. Andrology. Obstetrics; Humans; Male; Male and female genital diseases. Gonadal dysgenesis. Hermaphroditism. Sex hormones resistance; Male genital diseases; Medical sciences; Ovarian Neoplasms - pathology; Ovarian Neoplasms - therapy; Sertoli Cell Tumor - pathology; Sertoli Cell Tumor - therapy; Tumors; Human; Sertoli cell; Lymph node; Testicular feminization; Sexual differentiation disorder; Malignant tumor; Metastasis; Male pseudohermaphroditism; Genital diseases; Case study; Pathology; Gonad; Young adult; Cytogenetics; Tumor; Clinical investigation; Male genital diseases
• ISSN: 0090-8258; 1095-6859
• DOI: 10.1006/gyno.1999.5540

A 26-year-old individual with androgen insensitivity syndrome was operated on for a 3200-g Sertoli cell tumor of the left gonad with retroperitoneal metastases. Six courses of bleomycin, etoposide, and cisplatin chemotherapy followed surgical treatment. Eighteen months after the initial surgery the patient is free of disease and in good health. The association of Sertoli cell tumor with androgen insensitivity syndrome is discussed and the relevant literature is briefly reviewed.